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安康康元醫藥科技有限公司

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大黃素Emodin

大黃素Emodin

所屬分類(lèi)：

口腔健康原料

關(guān)鍵詞：

醫藥，食品，飲料和膳食補充劑、獸用植物添加劑

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產(chǎn)品描述

大黃素化學(xué)名：1'3'8-三羥基-6-甲基蒽醌

分子式：C15H10O5

分子量：270.23

CAS號：518-82-1

EINECS號：208-258-8

InChI：InChI=1/C15H10O5/c1-6-2-8-12(10(17)3-6)15(20)13-9(14(8)19)4-7(16)5-11(13)18/h2-5,16-18H,1H3

來(lái)源：為蓼科植物虎杖的干燥根莖和根。掌葉大黃的根莖，屬植物型藥劑。

規格：（50%，80%，98%)物理性質(zhì)：橙黃色長(cháng)針狀結晶(丙酮中結晶為橙色,甲醇中結晶為黃色)，熔點(diǎn)256℃～257℃。具有蒽醌的特殊反應。幾乎不溶于水，溶于乙醇及堿溶液。大黃素對金黃色葡萄球菌209P、鏈球菌、白喉桿菌、枯草桿菌、副傷寒桿菌、痢疾桿菌、大腸桿菌、流感桿菌、肺炎球菌、卡他球菌等均有抑制作用；對臨床常見(jiàn)厭氧性細菌有較強的抑制作用；其MIC略高于甲硝唑，在8μg/ml濃度能使76%~91%的厭氧菌生長(cháng)受抑。大黃素抗菌作用機制與抑制線(xiàn)粒體呼吸鏈電子傳遞、抑制呼吸與氨基酸、糖和蛋白質(zhì)代謝中間產(chǎn)物的氧化和脫氫等有關(guān)。抑制核酸和蛋白質(zhì)合成的最終結果，使細菌生長(cháng)受抑。

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安康康元醫藥科技有限公司

專(zhuān)業(yè)從事秦巴山脈道地中藥材有效成分提取，生產(chǎn)，銷(xiāo)售的高新技術(shù)植物化工企業(yè)

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